Final Data from AlloVir’s Phase 2 Study of Posoleucel for Multi-Virus Prevention to be Highlighted in Oral Presentation at 64th American Society of Hematology Annual Meeting
AlloVir, Inc. (Nasdaq: ALVR), a late-clinical stage allogeneic T-cell immunotherapy company, today announced that final data from the Phase 2 study of posoleucel for the prevention of clinically significant infections or diseases by multiple viruses following allogeneic hematopoietic cell transplantation (allo-HCT) has been accepted as an oral presentation at the 64th American Society of Hematology (ASH) Annual Meeting to be held in New Orleans, Louisiana, December 10-13, 2022. The presentation will include final efficacy and safety results as well as posoleucel expansion and persistence data
WALTHAM, Mass.--(BUSINESS WIRE)--Nov 3, 2022--
AlloVir, Inc. (Nasdaq: ALVR), a late-clinical stage allogeneic T-cell immunotherapy company, today announced that final data from the Phase 2 study of posoleucel for the prevention of clinically significant infections or diseases by multiple viruses following allogeneic hematopoietic cell transplantation (allo-HCT) has been accepted as an oral presentation at the 64th American Society of Hematology (ASH) Annual Meeting to be held in New Orleans, Louisiana, December 10-13, 2022. The presentation will include final efficacy and safety results as well as posoleucel expansion and persistence data.
Posoleucel is AlloVir’s lead investigational virus-specific T cell (VST) therapy being developed as an off-the-shelf therapeutic for the treatment or prevention of up to six devastating viruses (adenovirus, BK virus, cytomegalovirus, Epstein-Barr virus, human herpesvirus-6 and JC virus) that have few to no effective treatment or prevention options and can be life-threatening for allo-HCT patients. These common viral infections present significant challenges in the management of allo-HCT patients, with the potential for prolonged hospitalization, increased risk for graft versus host disease (GVHD), end-organ damage and death. Preventing these viral infections and diseases – whether through the prophylaxis of patients at high risk for viral reactivation or through the preemptive treatment of patients with viral reactivation who have not yet developed clinically significant infections or disease – has the potential to fundamentally transform the treatment landscape for allo-HCT.
“We are excited to share the final data from our Phase 2 study of posoleucel for multi-virus prevention, which continue to support the transformational potential of posoleucel. Based on preliminary data from this study, AlloVir initiated a global Phase 3 multi-virus prevention study earlier this year. We are pleased with the enthusiasm we are seeing from leading transplant centers around the world participating in the trial,” said Diana Brainard, M.D., CEO, AlloVir.
