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Clearing Brain Waste
This undated photo provided by the Oregon Health & Science University in October 2024 shows Drs. Erin Yamamoto, left, and Juan Piantino, who used special imaging to spot a long-suspected pathway the human brain uses to clear waste. (Christine Torres Hicks/OHSU via AP)

A peek inside human brain shows a way it cleans out waste

A unique peek inside the human brain may help explain how it clears away waste like the kind that leads to Alzheimer's disease

By LAURAN NEERGAARD
Published - Oct 07, 2024, 05:57 PM ET
Last Updated - Oct 07, 2024, 05:57 PM EDT

WASHINGTON (AP) — A unique peek inside the human brain may help explain how it clears away waste like the kind that can build up and lead to Alzheimer’s disease.

Brain cells use a lot of nutrients which means they make a lot of waste. Scientists have long thought the brain has special plumbing to flush out cellular trash, especially during sleep – they could see it happening in mice. But there was only circumstantial evidence of a similar system in people.

Now researchers have finally spotted that network of tiny waste-clearing channels in the brains of living people, thanks to a special kind of imaging.

“I was skeptical,” said Dr. Juan Piantino of Oregon Health & Science University, whose team reported the findings Monday. “We needed this piece to say this happens in humans, too.”

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