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The randomized, double-blind, placebo-controlled, Phase 2 clinical trial is expected to enroll 75 patients in North America and will assess the efficacy and safety of eblasakimab in dupilumab experienced patients who have discontinued their treatment for any reason, including inadequate disease control, loss of access to drug or an adverse event

ASLAN Pharmaceuticals Announces First Patient Screened in Study of Eblasakimab in Dupilumab ...

ASLAN Pharmaceuticals (Nasdaq: ASLN), a clinical-stage, immunology-focused biopharmaceutical company developing innovative treatments to transform the lives of patients, today announced that it has screened the first patient in its TREK-DX study of eblasakimab in adult patients with moderate-to-severe atopic dermatitis (AD) who have previously been treated with dupilumab. Eblasakimab is a potential first-in-class monoclonal antibody targeting the IL-13 receptor that has the potential to deliver a differentiated efficacy and safety profile

By ASLAN PHARMACEUTICALS LIMITED
Published - Dec 15, 2022, 07:06 AM ET
Last Updated - Apr 29, 2024, 04:14 AM EDT
  •  The TRials with EblasaKimab in Dupilumab eXperienced atopic dermatitis patients (TREK-DX) study will evaluate eblasakimab in a patient population with few safe treatment options
  • The study will enroll 75 patients in North America with topline results expected in the first quarter of 2024
  • Study is fully funded with no impact on previously reported cash runway
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